Kinomescan panel

2019-12-07 10:22

DiscoveRxs KINOME scan service provides the industrys fastest and most comprehensive kinase inhibitor testing. DiscoveRx is also the highest rated provider of kinase testing and offers options to profile compounds using a broad panel of 489 assays.The KINOMEscan platform employs a novel and proprietary active sitedirected competition binding assay to quantitatively measure interactions between test compounds and more than 480 kinase assays. The largest commercial kinase panel available, scanMAX panel, contains a set of 468 kinases covering AGC, CAMK, CMGC, CK1, STE, TK, TKL, lipid and atypical kinase families, plus important mutant forms. kinomescan panel

Panels Overview& Assay Principle Compounds that bind the kinase active site and directly (sterically) or indirectly (allosterically) prevent kinase binding to the immobilized ligand, will reduce the amount of kinase captured on the solid support (Panels A& B).

scanMAX Kinase Assay Panel The scan MAX service leverages a panel of 468 kinases covering AGC, CAMK, CMGC, CK1, STE, TK, TKL, lipid and atypical kinase families, plus important mutant forms. scanMAX is an ideal choice for all stages of drug discovery and development, to identify the most selective drug candidates from the largest collection of wildtype kinase assays. KINOMEscan enables you to quantitatively measure interactions between test compounds and more than 480 kinase assays including clinically relevant mutants, lipid, atypical, and pathogen kinases, plus a growing panel of activationstate specific assays.kinomescan panel KINOMEscan Worlds Largest Kinase Assay Panel The KINOME scan platform employs a novel and proprietary active sitedirected competition binding assay to quantitatively measure interactions between test compounds and more than 480 kinase assays including clinically relevant mutants, lipid, atypical, and pathogen kinases, plus a growing panel of activationstate specific assays.

Kinomescan panel free

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